Analisi real-world della epidemiologia e della gestione terapeutica dei pazienti affetti da fibrosi polmonare idiopatica in un contesto di pratica clinica italiana
La fibrosi polmonare idiopatica (IPF) è spesso diagnosticata tardivamente, con conseguente ritardo nell’inizio di terapie in grado di rallentare la progressione di malattia e il declino della funzione polmonare. Lo studio, condotto in un setting di reale pratica clinica italiana, ha valutato l’impatto dell’intervallo diagnostico di IPF sul burden clinico ed economico della patologia, focalizzandosi su epidemiologia, pattern terapeutico,… Leggi tutto »Analisi real-world della epidemiologia e della gestione terapeutica dei pazienti affetti da fibrosi polmonare idiopatica in un contesto di pratica clinica italiana
A real-world analysis of outcomes and healthcare costs of patients on perindopril/indapamide/amlodipine single-pill vs. multiple-pill combination in Italy
This analysis compared adherence, cardiovascular (CV) events and all-cause mortality incidence, and healthcare costs among hypertensive patients treated with perindopril (PER)/indapamide (IND)/amlodipine (AML) in single-pill combination (SPC) vs. multiple-pill combination, in a real-world setting in Italy. In this observational retrospective analysis of Italian administrative databases, adult patients treated with PER/IND/AML between 2010 and 2020 were… Leggi tutto »A real-world analysis of outcomes and healthcare costs of patients on perindopril/indapamide/amlodipine single-pill vs. multiple-pill combination in Italy
Profile, Healthcare Resource Consumption and Related Costs in ANCA-Associated Vasculitis Patients: a Real-World Analysis in Italy
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare autoimmune diseases triggeringinflammation of small vessels. This real-world analysis was focused on the most common AAV forms, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), to describe patients’ demographic and clinical characteristics,therapeutic management, disease progression, and the related economic burden. A retrospective analysis was conducted on administrative… Leggi tutto »Profile, Healthcare Resource Consumption and Related Costs in ANCA-Associated Vasculitis Patients: a Real-World Analysis in Italy
A retrospective analysis of treatment patterns, drug discontinuation and healthcare costs in Crohn’s disease patients treated with biologics
Background/aims: This real-world analysis evaluated the persistence and direct healthcare costs of Crohn’s Disease (CD) patients treated with biologics in Italy. Methods: A retrospective analysis on administrative databases of Italian healthcare entities, covering 10.4 million residents, was performed. Adult CD patients under biologics between 2015 and 2020 were in- cluded and attributed to first/second treatment… Leggi tutto »A retrospective analysis of treatment patterns, drug discontinuation and healthcare costs in Crohn’s disease patients treated with biologics
Characteristics and drug utilization of patients with hereditary angioedema in Italy, a real world-analysis
This real-world analysis investigated the characteristics and treatment patterns of patientswith hereditary angioedema (HAE) in Italy using the administrative data of health units across Italy.Patients were identified via exemption code or HAE-specific treatments (thus, all known forms, typeI, II and, III, were included). The index date was that of first prescription of HAE treatments withinthe… Leggi tutto »Characteristics and drug utilization of patients with hereditary angioedema in Italy, a real world-analysis
Real-world analysis of the economic and therapeutic burden in advanced breast cancer patients in Italy
Background: This real-world analysis evaluated drug utilization focusing on wastage and healthcare costsfor treatment of patients with advanced breast cancer (aBC) hormone receptor-positive (HR+)/humanepidermal growth factor receptor-2 negative (HER2-) in Italy.Methods: A retrospective analysis was conducted on administrative data covering about 13.3 millionhealth-assisted individuals. Across January/2017–June/2021, all patients with HR+/HER2-aBC wereidentified by ≥ 1 prescription… Leggi tutto »Real-world analysis of the economic and therapeutic burden in advanced breast cancer patients in Italy
Real-world Evaluation of the Management, Treatment Pathways and Outcome of Melanoma Patients with Target Therapies in Italy
In recent years, an increasing trend in the incidence of melanoma has been observed in Europe. Although early diagnosis and prompt intervention with local resection often results in positive outcomes, conversely, metastatic disease is still clinically challenging with a poor prognosis and a 5-year survival of around 30%. The growing awareness of melanoma biology and… Leggi tutto »Real-world Evaluation of the Management, Treatment Pathways and Outcome of Melanoma Patients with Target Therapies in Italy
La gestione terapeutica ed i costi sanitari associati in pazienti con malattie infiammatorie croniche intestinali (MICI): dati di real-world della regione Lazio
La presente analisi retrospettiva è stata condotta al fine di fornire evidenze di pratica clinica sulla gestione dei pazienti affetti da malattie infiammatorie croniche intestinali (MICI) in trattamento biologico. L’analisi si è basata sui dati amministrativi di un campione di ASL della Regione Lazio. Tra il Gennaio/2011-Settembre/2021 sono stati identificati i pazienti con diagnosi di MICI e… Leggi tutto »La gestione terapeutica ed i costi sanitari associati in pazienti con malattie infiammatorie croniche intestinali (MICI): dati di real-world della regione Lazio
Hypertriglyceridemia is associated with decline of estimated Glomerular filtration rate and risk of end-stage kidney disease in a real-word Italian cohort: Evidence from the TG-RENAL Study
Background: This analysis investigated the role of hypertriglyceridemia on renal function decline and developmentof end-stage kidney disease (ESKD) in a real-world clinical setting.Methods: A retrospective analysis using administrative databases of 3 Italian Local Health Units was performedsearching patients with at least one plasma triglyceride (TG) measurement between 2013 and June 2020,followed-up until June 2021. Outcome… Leggi tutto »Hypertriglyceridemia is associated with decline of estimated Glomerular filtration rate and risk of end-stage kidney disease in a real-word Italian cohort: Evidence from the TG-RENAL Study
Incidence and Predictors of Switching and Dose Change of Direct Oral Anticoagulants among Elderly Patients with Nonvalvular Atrial Fibrillation: A 5-Year Analysis of a Large Administrative Database
In the last decade, novel oral anticoagulants (NOACs) have emerged as prominent therapeutic options in non-valvular atrial fibrillation (NVAF). We analysed the clinical burden and the switching rate between all available NOACs, and their dosage change over a period of 5 years in a representative population of patients with NVAF aged between 70 and 75… Leggi tutto »Incidence and Predictors of Switching and Dose Change of Direct Oral Anticoagulants among Elderly Patients with Nonvalvular Atrial Fibrillation: A 5-Year Analysis of a Large Administrative Database
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