Global & Regional Health Technology Assessment

Impatto clinico ed economico dell’emicrania in Italia: un’analisi di real-world evidence

Introduction: This retrospective observational analysis evaluated the clinical, demographic, and economic burdenof migraine patients in real-world Italian clinical practice.Methods: A retrospective observational analysis was conducted using Italian administrative databases, involvingapproximately 12 million beneficiaries. All adult patients with at least one hospital discharge diagnosis ofmigraine (ICD-9-CM = 346) or at least one prescription for migraine-specific medications… Read More »Impatto clinico ed economico dell’emicrania in Italia: un’analisi di real-world evidence

The economic impact of multimorbidity in Italy:evaluation of direct costs and scenario analysis ofpatients with type 2 diabetes, heart failure, andchronic kidney disease using real-world data

ABSTRACTObjectives: This study aimed to evaluate the healthcare costs associated with managing type 2 diabetes (T2D),chronic kidney disease (CKD), and heart failure (HF) in Italy. Specifically, the research investigated the economicimpact on the Italian National Health System due to the increased clinical complexity and multimorbidity amongpatients with these conditions.Methods: A predictive model was developed to… Read More »The economic impact of multimorbidity in Italy:evaluation of direct costs and scenario analysis ofpatients with type 2 diabetes, heart failure, andchronic kidney disease using real-world data

RWE in oncologia: uso dei database per identificare isottotipi molecolari del cancro mammario metastatico in Italia

Introduction: The use of Real-World Evidence (RWE) is gaining increasing relevance in oncology, offering a complementaryperspective to randomised clinical trials (RCTs). In Italy, administrative databases represent a promisingsource to explore treatment patterns and distribution of molecular subtypes in metastatic breast cancer(mBC). This study was aimed at evaluating the feasibility and accuracy of using administrative data… Read More »RWE in oncologia: uso dei database per identificare isottotipi molecolari del cancro mammario metastatico in Italia

Differenze di genere e ipercolesterolemia: evidenze real-world dallo studio WECARE (Women Effective CArdiovascular Risk Evaluation)

Gender differences and hypercholesterolemia: real-world evidence from the study WECARE (Women EffectiveCArdiovascular Risk Evaluation)Introduction: The therapeutic control of LDL-cholesterol is essential in cardiovascular prevention, as recommendedby the recent guidelines.Objective: To evaluate gender differences in terms of demographic and clinical characteristics, treatment pattern,treatment adherence and healthcare costs in patients on lipid-lowering therapy, stratified by cardiovascular riskin… Read More »Differenze di genere e ipercolesterolemia: evidenze real-world dallo studio WECARE (Women Effective CArdiovascular Risk Evaluation)